Endocrine Abstracts

Background: Women affected by polycystic ovary syndrome (PCOS) frequently suffer from obesity, insulin resistance and impaired glucose tolerance. There is evidence showing an association of hypovitaminosis D with metabolic disturbances in PCOS women. We aimed to investigate the influence of vitamin D supplementation on metabolic and endocrine parameters in PCOS women.Design: Forty-eight women with PCOS were included in the study. Cholecalciferol was admi...

Objective: Studies in rodents indicate a role of vitamin D in male reproduction but the relationship between vitamin D and androgen levels in men is largely unexplored. We aimed to investigate the association of 25-hydroxyvitamin D [25(OH)D] levels with testosterone, FAI (free androgen index), and SHBG. Moreover, we examined whether androgen levels show a similar seasonal variation to 25(OH)D.Design: In this cross-sectional study, 25(OH)D, testosterone, ...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting about 5-10% of women. PCOS is characterized by hyperandrogenism, ovulatory disturbances, and polycystic ovaries. Many women with PCOS present with insulin resistance and central obesity and are at an increased risk for developing diabetes and cardiovascular disorders. Vitamin D deficiency is an important pathogenetic factor in the development of type II diabetes. The aim of the study was to...

Objective: Central obesity plays a major role in the pathophysiology of polycystic ovary syndrome (PCOS). However, little information exists concerning the impact of subcutaneous adipose tissue (SAT) on metabolic disturbances in PCOS. The aim of this study was to investigate whether SAT topography influences insulin resistance, impaired glucose tolerance, and metabolic parameters in PCOS women.Design: Prospective case-control trial.<p class="abstext"...